Serum specific IgE responses to inhalant allergens sensitization

Immune Responses to Inhalant Allergens

This overview describes the nature of the immune responses induced by the inhalation of allergens. There is a dichotomy in that B cells have multiple mechanisms that limit the amount of immunoglobulin E (IgE) antibody production, whereas T-cell responses are large even in nonallergic subjects. With the possible exception of responses to cat allergen, however, T cells from nonallergic subjects h...

Immune Responses to Inhalant Mammalian Allergens

In Europe and the USA, at least one person in four is exposed every day to inhalant allergens of mammalian origin, a considerable number is regularly exposed for professional reasons and almost everyone is occasionally exposed to inhalant allergens from pets or domestic animals. The production of IgE to these inhalant allergens, often complicated by asthma and rhinitis, defines the atopic statu...

Predictive Accuracy of Total IgE in Detection of Inhalant Allergens Sensitization

Background: The role of total IgE (TIGE) in detecting inhalant allergens (IA) sensitization in asthmatics is controversial and frequently underestimated. Objective: To test the relationship between TIGE and IA sensitization in asthmatics. Methods: One year duration cross-sectional study commencing from January in 2014. 118 asthmatics with mean age of 30±15 years collected from King Abdulaziz Un...

Allergen-specific IgE to inhalant and food allergens and total IgE values in China: comparison of 2 commercial immunoassays.

IgE sensitization to inhalant allergens and the risk of airway infection and disease: A population-based study

BACKGROUND Immunoglobulin E (IgE) sensitization, which is the propensity to develop IgE antibodies against common environmental allergens, is associated with a lymphocyte T-helper type 2 (Th2) skewed immune response and a high risk of allergic respiratory disease. Little is known about whether IgE sensitization confers an increased risk of respiratory infections in adults. We investigated the a...